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What is indole-3-carbinol

Indole-3-carbinol is a natural substance that is contained, for example, in vegetables from the cabbage family (especially broccoli, turnip cabbage, kale, white cabbage, cauliflower, red cabbage, etc.).

The dispelled and highly purified indole-3-carbinol (>98%) from Cosomed is obtained from cabbage family plants (broccoli, white cabbage, etc.). One packet of intdole-3-carbinol contains 60 capsules, each with 250mg indole-3-carbinol.

What is indole-3-carbinol used for

Indole-3-carbinol functions as an antioxidant and anti carcinogen, which has been backed up by studies. It has been seen that indole-3-carbinol functions as a chemoprevention and can slow the growth of mamma tumor cells.

Additional positive effects of indole-3-carbinol include:

  • Acceleration of detoxification of many potentially damaging chemicals (including carcinogens)
  • Antioxidant support
  • Blocks the overproduction of certain hormones, which can contribute to an increased risk of breast and prostate cancer

Indole-3-Carbinol studies

Brew Int J Cancer PMC 2012 July 19
Indole-3-carbinol inhibits MDA-MB-231 breast cancer cell motility and induces stress fibers and focal adhesion formation by activation of Rho kinase activity

Galluzi PLoS One. 2012; 7(8): e43249
Induction of Endoplasmic Reticulum Stress Response by the Indole-3-Carbinol Cyclic Tetrameric Derivative CTet in Human Breast Cancer Cell Lines

Marconett Carcinogenesis. 2011 September; 32(9): 1315–1323
Indole-3-carbinol downregulation of telomerase gene expression requires the inhibition of estrogen receptor-alpha and Sp1 transcription factor interactions within the hTERT promoter and mediates the G1 cell cycle arrest of human breast cancer cells

Weng Cancer Lett. 2008 April 18; 262(2): 153
Indole-3-carbinol as a chemopreventive and anti-cancer agent

Garikapaty et al. Oncol Rep. 2005 Jan;13(1):89-93
Anti-carcinogenic and anti-metastatic properties of indole-3-carbinol in prostate cancer

Bell, et al. Gynecol Oncol. 2000 Aug;78(2):123-9
Placebo-controlled trial of indole-3-carbinol in the treatment of CIN

Wong et al. J Cell Biochem Suppl. 1997;28-29:111-6
Dose-ranging study of indole-3-carbinol for breast cancer prevention

Grubbs et al. Anticancer Res. 1995 May-Jun;15(3):709-16
Chemoprevention of chemically-induced mammary carcinogenesis by indole-3-carbinol

Indole-3-Carbinol articles

Tumorprävention mit Brokkoli und Kohl

Gemüse gegen den Krebs. Glucosinolat Indol-3-Carbinol

Magazin: Europanews.Org
Heilkraft Des Broccoli Calabrese

Wie schützt Brokkoli vor Tumoren?

How Cruciferous Vegetables And Their Indole-3-Carbinol Content Help Reduce Cancer Risk

Cosomed GmbH - About the manufacturer

Logo Cosomed

Stability and performance of the immune system have a substantial role for our well-being. The body's defenses are an important factor in preventing, relieving, and healing illnesses. That is why Cosomed is devoted to researching new and unique products to strengthen and stabilize the immune system.

We invest a great deal of time and money in order to identify individual substances from the scientific findings of cancer research that might be the foundation for new dietary supplements.
Through sophisticated procedures, individual substances such as these can be highly purified and marketed even today as dietary supplements.
The combination of scientific foundation and highest purity leads to products based on the requirements for medicines.

That is how we create a novel and unique range of products for health-conscious people. Our products can be used for prevention and concomitant support of therapeutic measures.

Recommended intake and safety instructions

Recommended intake
One capsule of indole-3-carbinol 250 mg twice daily. Do not exceed the indicated recommended daily intake.

Indol-3-Carbinol, mikrokristalline Cellulose, Gelatine

Safety instructions
Dietary supplements are not a substitute for a balanced and varied diet. Keep out of reach of children. Store in a cool and dry location. The capsules do not contain coatings, are free of lactose, gluten, dyes, and flavoring.

Apigenin Grapefruit

Order your monthly dosage with 60 capsules à 250 mg now - with free shipping!